marijuana or placebo?
An add-on design in which smoked marijuana or placebo would be administered to incomplete responders to standard combination therapy would be appropriate. A dronabinol capsule group should also be included white widow feminized. Stratification should be done for naive versus experienced marijuana smokers. Nausea severity, vomiting prevention, and CNS effects assessments should be primary endpoints. Inhaled marijuana merits testing in controlled, double-blind, randomized trials for the above indications.